Can Hose for food substances requiring the highest purity PHARMAFLON be sterilized (steam, autoclave, or chemical) without degrading the MFA inner layer or compromising compliance with FDA and USP Class VI?

Hose for food substances requiring the highest purity PHARMAFLON Format can be sterilized, but with conditions to preserve the MFA inner layer and regulatory compliance. Steam/autoclave: MFA (fluoropolymer) is broadly resistant to high temperatures (operating up to +170Â°C) and compatible with steam sterilization in many applications; however, repeated autoclaving at excessive temperature/pressure or improper fitting/clamping that abrades or deforms the inner layer can damage the MFA and compromise USP Class VI suitability. Use validated autoclave cycles within the hose temperature rating, avoid sharp-edged fittings, and ensure electrical continuity and mechanical integrity after sterilization. Chemical sterilization: compatible chemical agents (e.g., hydrogen peroxide vapor, peracetic acid, ethylene oxide) are generally acceptable for fluoropolymers, but each sterilant must be validated for compatibility with MFA, EPDM outer layer, bonding points, and certification retention (FDA/EC/USP). Follow manufacturer validation: use smooth spigot fittings matched to hose ID, clamp sleeves or shell clamps as specified, and avoid oversized or ribbed fittings that could cut the inner layer. In summary: sterilization is possible (steam/autoclave and appropriate chemical methods) if done within the hoseâs thermal/mechanical limits, with correct installation and validated cycles to ensure the MFA inner layer and compliance with FDA and USP Class VI remain intact.

Can Hose for food substances requiring the highest purity PHARMAFLON be used with CIP/SIP procedures without damaging the MFA inner layer or losing regulatory compliance?

Hose for food substances requiring the highest purity PHARMAFLON Format can be used with CIP/SIP procedures without damaging the MFA (PTFE-like) inner layer or losing regulatory compliance, provided correct conditions are met. Its inner smooth fluoropolymer MFA is chemically and thermally resistant (operating â50Â°C to +170Â°C) and complies with FDA 21 CFR 177.1550, EU 10/2011 and USP Class VI, supporting pharmaceutical and food GMP. To avoid damage and maintain compliance, use smooth spigot fittings precisely matched to the hose ID, avoid sharp ribs, and install with clamp sleeves/shell clamps as specified. Ensure CIP/SIP temperatures and chemicals remain within the hoseâs rated limits and follow manufacturer cleaning cycle recommendations. Regular inspection of fittings, continuity (copper wires), and seals is required to preserve integrity and traceability.

Is Hose for food substances requiring the highest purity PHARMAFLON compatible with common pharmaceutical sterilants (e.g., hydrogen peroxide, peracetic acid)?

Hose for food substances requiring the highest purity PHARMAFLON Format is generally compatible with common pharmaceutical sterilants such as hydrogen peroxide and peracetic acid, with important caveats. Why compatible: - Inner layer is smooth MFA (fluoropolymer), which offers excellent chemical resistance to strong oxidizers including hydrogen peroxide and peracetic acid in typical concentrations used for pharmaceutical sterilization. - Construction and materials meet stringent food and pharmaceutical standards (10/2011/EC, FDA 21 CFR 177.1550, USP Class VI), indicating suitability for high-purity and aseptic applications. - Wide temperature range (-50Â°C to +170Â°C) covers thermal conditions used during many sterilization cycles. Caveats and recommendations: - Verify sterilant concentration, temperature and exposure time against MFA chemical resistance data and your process conditions before use. Very high concentrations, prolonged exposure, elevated temperatures or catalysts can accelerate degradation of polymers. - Check compatibilty of other components (sealants, fittings, clamp sleeves, copper wires) with chosen sterilant. - Follow installation guidance (smooth fittings, correct spigot diameter, clamp sleeves) to avoid mechanical damage that could compromise sterilant resistance. - Perform validation and periodic inspection (visual, integrity and extractables testing) after sterilization cycles to confirm no damage, leaching or performance loss. Conclusion: PHARMAFLON Formatâs MFA inner layer is appropriate for common pharmaceutical sterilants in normal use, but confirm specific sterilization parameters and validate in your process prior to routine use.

Hose for food substances requiring the highest purity PHARMAFLON

All products, Food and beverage hoses/

Additional information

Material	PFA/MFA/FEP – fluoropolymer
Maximum operating temperature [°C]	170
Minimum operating temperature [°C]	-50
Vacuum resistance	yes
Standard length [m]	20, 30, 5, 60
Reinforcement	steel spiral, synthetic cover

Suction and discharge hose intended for the transfer of pharmaceutical products, cosmetics, food substances, and chemicals (selection according to the principles in the chapter “Chemical Hoses”). It does not contain plasticizers, phthalates, or animal-derived substances. It is characterized by high thermal and mechanical strength. It is an excellent solution for processing industries requiring the highest safety during the transfer of high-purity products. The outer layer is resistant to abrasion, ozone, and weather conditions. It has two copper wires ensuring electrical continuity between the hose ends. Standards and requirements: 1) General EC 2002/95 (RoHS), EC 1907/2006 (REACH). 2) Food industry, contact with food 1935/2004/EC and 2023/2006/EU (GMP). The inner layer complies with 10/2011/EC, D.M. 21/03/73, FDA 21 CFR 177.1550. The outer layer complies with FDA 21 CFR 177.2600, D.M. 21/03/73. 3) Pharmaceutical industry USP Class VI (inner layer). Installation: use smooth fittings with a spigot (“tail” to the hose) that do not have sharp or high ribs that could cut or damage the inner layer made of MFA when tightened. The diameter of the spigot should be precisely matched to the diameter of the hose to ensure tightness. Installation with clamp sleeves or shell clamps. Inner layer: smooth fluoropolymer MFA. Reinforcement: synthetic cord, steel spiral. Outer layer: smooth EPDM rubber. Working pressure: 10 bar. Vacuum: 0.9 bar. Operating temperature: -50°C to +170°C (for most chemicals).

List of product variants

Article number	Product variant name	DN	BAR	Availability	Actions
MT-PHARMA-100	PHARMAFLON hose 100x116 mm	100	10	In stock	Enquiry
MT-PHARMA-13	PHARMAFLON hose 13x25 mm	12	10	In stock	Enquiry
MT-PHARMA-19	PHARMAFLON hose 19x31 mm	20	10	In stock	Enquiry
MT-PHARMA-25	PHARMAFLON hose 25x37 mm	25	10	In stock	Enquiry
MT-PHARMA-32	PHARMAFLON hose 32x45 mm	32	10	In stock	Enquiry
MT-PHARMA-38	PHARMAFLON hose 38x51 mm	38	10	In stock	Enquiry
MT-PHARMA-51	PHARMAFLON hose 51x65.5 mm	50	10	In stock	Enquiry
MT-PHARMA-63	PHARMAFLON hose 63.5x79.5 mm	65	10	In stock	Enquiry
MT-PHARMA-76	PHARMAFLON hose 76x92 mm	75	10	In stock	Enquiry

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Suction and discharge hose intended for the transfer of pharmaceutical products, cosmetics, food substances, and chemicals (selection according to the principles in the chapter “Chemical Hoses”). It does not contain plasticizers, phthalates, or animal-derived substances. It is characterized by high thermal and mechanical strength. It is an excellent solution for processing industries requiring the highest safety during the transfer of high-purity products. The outer layer is resistant to abrasion, ozone, and weather conditions. It has two copper wires ensuring electrical continuity between the hose ends. Standards and requirements: 1) General EC 2002/95 (RoHS), EC 1907/2006 (REACH). 2) Food industry, contact with food 1935/2004/EC and 2023/2006/EU (GMP). The inner layer complies with 10/2011/EC, D.M. 21/03/73, FDA 21 CFR 177.1550. The outer layer complies with FDA 21 CFR 177.2600, D.M. 21/03/73. 3) Pharmaceutical industry USP Class VI (inner layer). Installation: use smooth fittings with a spigot (“tail” to the hose) that do not have sharp or high ribs that could cut or damage the inner layer made of MFA when tightened. The diameter of the spigot should be precisely matched to the diameter of the hose to ensure tightness. Installation with clamp sleeves or shell clamps. Inner layer: smooth fluoropolymer MFA. Reinforcement: synthetic cord, steel spiral. Outer layer: smooth EPDM rubber. Working pressure: 10 bar. Vacuum: 0.9 bar. Operating temperature: -50°C to +170°C (for most chemicals).

Additional information

Material	PFA/MFA/FEP – fluoropolymer
Maximum operating temperature [°C]	170
Minimum operating temperature [°C]	-50
Vacuum resistance	yes
Standard length [m]	20, 30, 5, 60
Reinforcement	steel spiral, synthetic cover